{"id":22587,"date":"2023-02-22T09:18:35","date_gmt":"2023-02-22T07:18:35","guid":{"rendered":"https:\/\/embryolab.eu\/?p=22587"},"modified":"2023-02-22T09:18:35","modified_gmt":"2023-02-22T07:18:35","slug":"paternal-age-and-reproduction","status":"publish","type":"post","link":"https:\/\/embryolab-new.demolink.gr\/el\/paternal-age-and-reproduction\/","title":{"rendered":"\u03a0\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae"},"content":{"rendered":"
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\u039c\u03b1\u03c1\u03b9\u0301\u03bd\u03b1 \u0394\u03b7\u03bc\u03b7\u03c4\u03c1\u03b1\u0301\u03ba\u03b7<\/a><\/p>\n

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MD, MSc, M.H.A., PhD, EFOG-EBCOG, \u0393\u03c5\u03bd\u03b1\u03b9\u03ba\u03bf\u03bb\u03bf\u0301\u03b3\u03bf\u03c2 \u03a5\u03c0\u03bf\u03b2\u03bf\u03b7\u03b8\u03bf\u03c5\u0301\u03bc\u03b5\u03bd\u03b7\u03c2 \u0391\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b7\u0301\u03c2,<\/p>\n

European Fellow of Reproductive Medicine ESHRE\/EBCOG, \u0391\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03c9\u0301\u03c4\u03c1\u03b9\u03b1 \u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03b7\u0301 \u0394\u03b9\u03b5\u03c5\u03b8\u03c5\u0301\u03bd\u03c4\u03c1\u03b9\u03b1 Embryolab<\/p>\n

 <\/p>\n

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\u03a4\u03bf \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u0301 \u03c1\u03bf\u03bb\u03bf\u0301\u03b9<\/strong><\/p>\n

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\u03c4\u03c9\u03bd 60. \u03a3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03b1\u0301\u03bd\u03c9 \u03c4\u03c9\u03bd 40 \u03c5\u03c0\u03b1\u0301\u03c1\u03c7\u03b5\u03b9 \u03c4\u03c1\u03b9\u03c0\u03bb\u03b1\u0301\u03c3\u03b9\u03b1 \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03bf\u0301\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bc\u03c6\u03b1\u0301\u03bd\u03b9\u03c3\u03b7\u03c2 \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u0301\u03b1\u03c2 \u03b5\u03ba\u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u0301\u03c4\u03b9\u03c3\u03b7\u03c2. \u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03b1\u0301 \u03bc\u03b5 \u03c4\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03bf\u0301 \u03b4\u03b9\u03b1\u0301\u03c3\u03c4\u03b7\u03bc\u03b1 \u03b5\u0301\u03c9\u03c2 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u0301\u03c4\u03b5\u03c5\u03be\u03b7 \u03ba\u03c5\u0301\u03b7\u03c3\u03b7\u03c2, \u03c4\u03b1 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03b1\u0301 \u03b4\u03b5\u03b4\u03bf- \u03bc\u03b5\u0301\u03bd\u03b1 \u03b4\u03b5\u03b9\u0301\u03c7\u03bd\u03bf\u03c5\u03bd 5 \u03c6\u03bf\u03c1\u03b5\u0301\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03bf\u0301\u03c4\u03b5\u03c1\u03bf \u03c7\u03c1\u03bf\u0301\u03bd\u03bf \u03bc\u03b5\u0301\u03c7\u03c1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u0301\u03c4\u03b5\u03c5\u03be\u03b7 \u03ba\u03c5\u0301\u03b7\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03b1\u0301\u03b4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03c9\u0301\u03bd \u03b1\u0301\u03bd\u03c9 \u03c4\u03c9\u03bd 45 \u03b5\u03c4\u03c9\u0301\u03bd \u03c3\u03b5 \u03c3\u03c7\u03b5\u0301\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03c5\u0301\u03c2 <25 \u03b5\u03c4\u03c9\u0301\u03bd (\u03b2\u03bb. \u03a0\u03b9\u0301\u03bd\u03b1\u03ba\u03b1 1) \u03ba\u03b1\u03b9 \u03b1\u03c5\u03c4\u03bf\u0301 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03b9\u0301\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b3\u03ba\u03c1\u03bf\u03c5\u03c0 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03c9\u0301\u03bd \u03bc\u03b5 \u03c0\u03bf\u03bb\u03c5\u0301 \u03bd\u03b5\u03bf\u0301\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c3\u03c5\u03bd\u03c4\u03c1\u03bf\u0301\u03c6\u03bf\u03c5\u03c2 (<25 \u03b5\u03c4\u03c9\u0301\u03bd) (\u0391raujo et al., 2004).<\/p>\n

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\u03a4\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03c9\u0301\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03b9\u0301\u03bd\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c5\u0301\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2;<\/h3>\n
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\u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b5\u0301\u03c2 \u03c3\u03c4\u03bf \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1:<\/strong> \u0397 \u03b5\u03c0\u03b9\u0301\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2 \u03c3\u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u0301\u03c4\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03b4\u03b9\u03b4\u03c5\u03bc\u03b9\u0301\u03b4\u03b1\u03c2 \u03c6\u03b1\u03b9\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03c5\u0301\u03bd \u03c4\u03b7 \u03b2\u03b1\u03c3\u03b9\u03ba\u03bf\u0301\u03c4\u03b5\u03c1\u03b7 \u03b1\u03b9\u03c4\u03b9\u0301\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c4\u03c9\u0301\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03b9\u0301\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u0301\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c3\u03c4\u03bf\u03bd \u03b1\u0301\u03bd\u03b4\u03c1\u03b1. \u0397 \u03c0\u03c4\u03c9\u0301\u03c3\u03b7 \u03b1\u03c5\u03c4\u03b7\u0301 \u03ba\u03c5\u03bc\u03b1\u03b9\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf 0.17%-0.8% \u03b1\u03bd\u03b1\u0301 \u03b5\u0301\u03c4\u03bf\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03b9\u03b1\u0301\u03c6\u03bf\u03c1\u03b5\u03c2 \u03bc\u03b5\u03bb\u03b5\u0301\u03c4\u03b5\u03c2, \u03b4\u03b7\u03bb\u03b1\u03b4\u03b7\u0301 3%-16% \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u0301\u03bf\u03b4\u03bf 20 \u03b5\u03c4\u03c9\u0301\u03bd. \u0391\u03bd\u03b1\u0301\u03bb\u03bf\u03b3\u03b7 \u03c0\u03c4\u03c9\u0301\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03b9\u0301\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03bf\u03bb\u03bf\u03b3\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2, \u03bc\u03b5 \u03c4\u03b1 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03b7\u0301\u03c2 \u03bc\u03bf\u03c1\u03c6\u03bf\u03bb\u03bf\u03b3\u03b9\u0301\u03b1\u03c2 \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03bf\u03b6\u03c9\u03b1\u0301\u03c1\u03b9\u03b1 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03c9\u0301\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 4%-18% \u03c3\u03b5 20 \u03c7\u03c1\u03bf\u0301\u03bd\u03b9\u03b1. \u039f \u03bf\u0301\u03b3\u03ba\u03bf\u03c2 \u03ba\u03b1\u03b8\u03c9\u0301\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u0301\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c6\u03b1\u03b9\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03bc\u03b5\u03b9\u03c9\u0301\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b9\u0301\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1: 90% \u03b1\u03c0\u03bf\u0301 \u03c4\u03b1 \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03b1\u0301 \u03c3\u03c9\u03bb\u03b7\u03bd\u03b1\u0301\u03c1\u03b9\u03b1 \u03c0\u03b5\u03c1\u03b9\u03b5\u0301\u03c7\u03bf\u03c5\u03bd \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u0301\u03b4\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03c9\u03bd 20-30 \u03ba\u03b1\u03b9 \u03bc\u03bf\u0301\u03bd\u03bf \u03c4\u03bf 50% \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 40-50 \u03b5\u03c4\u03c9\u0301\u03bd. \u039c\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03b9\u0301\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b1\u0301\u03bb\u03bb\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03b1\u0301 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2. \u0397 \u03b3\u03bb\u03c5\u03ba\u03bf\u03c3\u03b9\u03b4\u03b1\u0301\u03c3\u03b7, \u03c4\u03bf PSA, \u03bf \u03c8\u03b5\u03c5\u03b4\u03b1\u0301\u03c1\u03b3\u03c5\u03c1\u03bf\u03c2, \u03b7 \u03c6\u03c1\u03bf\u03c5\u03ba\u03c4\u03bf\u0301\u03b6\u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03b1\u0301\u03b6\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03b7\u0301 \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u0301\u03bd\u03b4\u03c1\u03b5\u03c2 >50 \u03b5\u03c4\u03c9\u0301\u03bd \u03c3\u03b5 \u03c3\u03c7\u03b5\u0301\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03c5\u0301\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03c5\u0301 21-30 \u03b5\u03c4\u03c9\u0301\u03bd \u03bb\u03bf\u0301\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03c0\u03c4\u03c9\u0301\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03bf\u0301\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03c9\u0301\u03bd \u03b1\u03b4\u03b5\u0301\u03bd\u03c9\u03bd (Harris et al., 2011).<\/p>\n

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\u039a\u03b1\u03c4\u03b1\u03ba\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u0301\u03c2 \u03c4\u03bf\u03c5 DNA \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 (DFI): <\/strong>\u039f \u03ba\u03b1\u03c4\u03b1\u03ba\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u0301\u03c2 \u03c4\u03bf\u03c5 DNA \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u0301\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03b9\u0301 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03b7\u0301 \u03c4\u03bf\u03c5 \u03b9\u03ba\u03b1\u03bd\u03bf\u0301\u03c4\u03b7\u03c4\u03b1. \u0391\u03c5\u0301\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03ba\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u03c5\u0301 \u03c4\u03bf\u03c5 DNA \u03b5\u0301\u03c7\u03b5\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b7\u03b8\u03b5\u03b9\u0301 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c5\u0301\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2. \u03a0\u03b9\u03b8\u03b1\u03bd\u03bf\u0301\u03c4\u03b1\u03c4\u03b1 \u03b1\u03c5\u03c4\u03bf\u0301 \u03bd\u03b1 \u03bf\u03c6\u03b5\u03b9\u0301\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c5\u0301\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03bf\u03c5\u0301 \u03c3\u03c4\u03c1\u03b5\u03c2 \u03bc\u03b5 \u03c4\u03bf \u03c7\u03c1\u03bf\u0301\u03bd\u03bf \u03b1\u03bb\u03bb\u03b1\u0301 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c4ou \u03b1\u03bd\u03c4\u03b9\u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03bf\u03c5\u0301 \u03c1\u03bf\u0301\u03bb\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03b4\u03b9\u03b4\u03c5\u03bc\u03b9\u0301\u03b4\u03b1\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 (Cocuzza et al., 2008).<\/p>\n

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\u03a5\u03b3\u03b5\u03b9\u0301\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u0301\u03bb\u03bb\u03bf\u03bd: <\/strong>\u039c\u03b5 \u03c4\u03b7 \u03b1\u03c5\u0301\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2 \u03b1\u03c5\u03be\u03b1\u0301\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03bf\u0301\u03c4\u03b7\u03c4\u03b1 \u03b5\u03bc\u03c6\u03b1\u0301\u03bd\u03b9\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03b1\u0301\u03c4\u03c9\u03bd \u03c5\u03b3\u03b5\u03b9\u0301\u03b1\u03c2 \u03b1\u03bb\u03bb\u03b1\u0301 \u03ba\u03b1\u03b9 \u03b5\u0301\u03ba\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03b5\u0301\u03c2 \u03c4\u03bf\u03be\u03b9\u0301\u03bd\u03b5\u03c2. \u0394\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03b7\u0301 \u03b5\u03c0\u03b9\u0301\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b4\u03c1\u03b9\u03ba\u03b7\u0301 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u0301\u03c4\u03b7\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03b9\u0301 \u03bd\u03b1 \u03b5\u0301\u03c7\u03b5\u03b9 \u03b7 \u03b9\u03bf\u03b3\u03b5\u03bd\u03b7\u0301\u03c2 \u03bf\u03c1\u03c7\u03b9\u0301\u03c4\u03b9\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03b5\u0301\u03ba\u03b8\u03b5\u03c3\u03b7 \u03c3\u03b5 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03c9\u0301\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b4\u03b9\u03b4\u03bf\u0301\u03bc\u03b5\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u0301\u03b2\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03b9\u03bf\u03c5\u0301\u03c2 \u03bb\u03bf\u0301\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03b7\u0301\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03c9\u0301\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u0301\u03c1\u03c9\u03bd, \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u0301\u03ba\u03bb\u03b7\u03c3\u03b7\u03c2 \u03b9\u03c3\u03c7\u03b1\u03b9\u03bc\u03b9\u0301\u03b1\u03c2, \u03b1\u03c0\u03bf\u0301\u03c6\u03c1\u03b1\u03be\u03b7\u03c2 \u03ba\u03b1\u03b8\u03c9\u0301\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u0301\u03c3\u03c9 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03b7\u0301\u03c2 \u03b1\u03c0\u03b1\u0301\u03bd\u03c4\u03b7\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03b7\u0301. \u03a7\u03c1\u03bf\u0301\u03bd\u03b9\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u0301\u03bd\u03b5\u03b9\u03b5\u03c2 \u03bf\u0301\u03c0\u03c9\u03c2 \u03b7 \u03c7\u03c1\u03bf\u0301\u03bd\u03b9\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03b7\u0301 \u03b1\u03bd\u03b5\u03c0\u03b1\u0301\u03c1\u03ba\u03b5\u03b9\u03b1, \u03b7 \u03ba\u03b9\u0301\u03c1\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b7\u0301\u03c0\u03b1\u03c4\u03bf\u03c2, \u03b7 \u03b4\u03c1\u03b5\u03c0\u03b1\u03bd\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03b7\u0301 \u03b1\u03bd\u03b1\u03b9\u03bc\u03b9\u0301\u03b1, \u03c0\u03b1\u03b8\u03b7\u0301\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03b5\u03c0\u03c4\u03b9\u03ba\u03bf\u03c5\u0301 \u03bc\u03c0\u03bf\u03c1\u03bf\u03c5\u0301\u03bd \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u0301\u03c3\u03bf\u03c5\u03bd \u03c5\u03c0\u03bf\u03b3\u03bf\u03bd\u03b1\u03b4\u03b9\u03c3\u03bc\u03bf\u0301 \u03c3\u03c4\u03bf\u03bd \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03b5\u03bd\u03c9\u0301 \u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03b7\u0301 \u03b1\u03b3\u03c9\u03b3\u03b7\u0301 \u03b3\u03b9\u03b1 \u03b1\u0301\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03b8\u03b7\u0301\u03c3\u03b5\u03b9\u03c2 (\u03c5\u03c0\u03b5\u0301\u03c1\u03c4\u03b1\u03c3\u03b7, \u03c8\u03c5\u03c7\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03b1\u0301 \u03bd\u03bf\u03c3\u03b7\u0301\u03bc\u03b1\u03c4\u03b1, \u03c0\u03b1\u03b8\u03b7\u0301\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u0301\u03c4\u03b7) \u03bc\u03c0\u03bf\u03c1\u03b5\u03b9\u0301 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03b5\u03c1\u03b5\u03b1\u0301\u03c3\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03b5\u0301\u03c4\u03c1\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2. \u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03b1\u0301 \u03bc\u03b5 \u03c4\u03bf \u03ba\u03b1\u0301\u03c0\u03bd\u03b9\u03c3\u03bc\u03b1,\u03b5\u03b9\u0301\u03bd\u03b1\u03b9 \u03c0\u03bb\u03b5\u0301\u03bf\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03bc\u03b5\u0301\u03bd\u03b7 \u03b7 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03b7\u0301 \u03c4\u03bf\u03c5 \u03b5\u03c0\u03b9\u0301\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03b5\u0301\u03c4\u03c1\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c0\u03b5\u0301\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 (\u0397arris et al., 2011).<\/p>\n

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\u0391\u03bd\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u0301\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b5\u0301\u03c2: <\/strong>\u039c\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03bc\u03b5\u03b9\u03c9\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bf \u03bf\u0301\u03b3\u03ba\u03bf\u03c2 \u03c4\u03c9\u03bd \u03bf\u0301\u03c1\u03c7\u03b5\u03c9\u03bd. \u039f\u03b9 \u03b1\u0301\u03bd\u03b4\u03c1\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd 8\u03b7 \u03b4\u03b5\u03ba\u03b1\u03b5\u03c4\u03b9\u0301\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03b7\u0301\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b5\u0301\u03c7\u03bf\u03c5\u03bd 31% \u03bc\u03b9\u03ba\u03c1\u03bf\u0301\u03c4\u03b5\u03c1\u03bf \u03bf\u0301\u03b3\u03ba\u03bf \u03bf\u0301\u03c1\u03c7\u03b5\u03c9\u03bd \u03b1\u03c0\u03bf\u0301 \u03b1\u03c5\u03c4\u03bf\u03c5\u0301\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03c9\u03bd 18-40 \u03b5\u03c4\u03c9\u0301\u03bd (Mahmoud et al., 2003). \u039c\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b5\u0301\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03c5\u0301\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u0301 \u03b5\u03c0\u03b9\u03b8\u03b7\u0301\u03bb\u03b9\u03bf (\u03bb\u03b5\u0301\u03c0\u03c4\u03c5\u03bd\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b4\u03bf\u03bc\u03c9\u0301\u03bd \u03c4\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b9\u0301\u03bd\u03c9\u03c3\u03b7), \u03c4\u03bf \u03bf\u03c0\u03bf\u03b9\u0301\u03bf \u03b5\u03b9\u0301\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03c5\u0301\u03b8\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03bf\u03b3\u03b5\u0301\u03bd\u03b5\u03c3\u03b7, \u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u0301\u03c2 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u0301\u03c1\u03c9\u03bd Leydig \u03ba\u03b1\u03b9 Sertoli \u03bc\u03b5\u03b9\u03c9\u0301\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03bd\u03c9\u0301 \u03b1\u03c5\u03be\u03b1\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03c3\u03c3\u03c9\u0301\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c7\u03c1\u03c9\u03c3\u03c4\u03b9\u03ba\u03b7\u0301\u03c2 \u03bb\u03b9\u03c0\u03bf\u03c6\u03bf\u03c5\u03c3\u03ba\u03b9\u0301\u03bd\u03b7\u03c2 (Harris et al., 2011).<\/p>\n

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\u039f\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03b5\u0301\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b5\u0301\u03c2:<\/strong> \u0397 \u03b5\u03c0\u03b9\u0301\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2 \u03c3\u03c4\u03bf\u03bd \u03b1\u0301\u03be\u03bf\u03bd\u03b1 \u03c5\u03c0\u03bf\u03b8\u03b1\u0301\u03bb\u03b1\u03bc\u03bf\u03c2 – \u03c5\u03c0\u03bf\u0301\u03c6\u03c5\u03c3\u03b7 – \u03bf\u0301\u03c1\u03c7\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b8\u03c9\u0301\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u03c5\u0301 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u0301\u03c1\u03c9\u03bd Leydig \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03b5\u0301\u03c7\u03bf\u03c5\u03bd \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u0301\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c4\u03c9\u0301\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03bb\u03b5\u03c5\u0301\u03b8\u03b5\u03c1\u03b7\u03c2 \u03c4\u03b5\u03c3\u03c4\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u0301\u03bd\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u0301 0.8% \u03ba\u03b1\u0301\u03b8\u03b5 \u03b5\u0301\u03c4\u03bf\u03c2. \u039c\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03b1\u0301\u03b6\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 DHEAS, DHEA, \u03ba\u03bf\u03c1\u03c4\u03b9\u03b6\u03bf\u0301\u03bb\u03b7 \u03ba\u03b1\u03b9 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u0301\u03bd\u03b7. \u03a3\u03c4\u03b7 \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c4\u03b5\u03c3\u03c4\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u0301\u03bd\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b1\u0301\u03bb\u03bb\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c7\u03c1\u03bf\u0301\u03bd\u03b9\u03b5\u03c2 \u03c0\u03b1\u03b8\u03b7\u0301\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b8\u03c9\u0301\u03c2 \u03ba\u03b1\u03b9 \u03bf \u03c5\u03c8\u03b7\u03bb\u03bf\u0301\u03c2 \u03b4\u03b5\u03b9\u0301\u03ba\u03c4\u03b7\u03c2 \u03bc\u03b1\u0301\u03b6\u03b1\u03c2 \u03c3\u03c9\u0301\u03bc\u03b1\u03c4\u03bf\u03c2 (\u0392\u039c\u0399) (Feldman et al., 2002).<\/p>\n

\n
\n
\n
\n

\u03a5\u03c0\u03bf\u03b2\u03bf\u03b7\u03b8\u03bf\u03c5\u0301\u03bc\u03b5\u03bd\u03b7 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b7\u0301<\/h3>\n
\n
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\u039f \u03c1\u03bf\u0301\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03b5\u0301\u03bd\u03b7\u03c2 \u03c0\u03b1\u03c4\u03c1\u03b9\u03ba\u03b7\u0301\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2 \u03b5\u03b9\u0301\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b1\u0301\u03bb\u03bf\u03b3\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03ba\u03c5\u0301\u03ba\u03bb\u03bf\u03c5\u03c2 \u03c5\u03c0\u03bf\u03b2\u03bf\u03b7\u03b8\u03bf\u03c5\u0301\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b7\u0301\u03c2. \u039c\u03b5\u03bb\u03b5\u0301\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03b5\u0301\u03bb\u03b1\u03b2\u03b1\u03bd \u03ba\u03c5\u0301\u03ba\u03bb\u03bf\u03c5\u03c2 \u03b5\u03bd\u03b4\u03bf\u03bc\u03b7\u0301\u03c4\u03c1\u03b9\u03b1\u03c2 \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b5\u0301\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2 (17.000 \u03ba\u03c5\u0301\u03ba\u03bb\u03bf\u03c5\u03c2 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u0301 \u03b1\u03c5\u03c4\u03b5\u0301\u03c2) \u03ba\u03b1\u03c4\u03b5\u0301\u03bb\u03b7\u03be\u03b1\u03bd \u03c3\u03c4\u03bf \u03c3\u03c5\u03bc\u03c0\u03b5\u0301\u03c1\u03b1\u03c3\u03bc\u03b1 \u03c0\u03c9\u03c2 \u03b7 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03b9\u0301 \u03c4\u03bf\u03bd \u03c0\u03b9\u03bf \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u0301 \u03c0\u03b1\u03c1\u03b1\u0301\u03b3\u03bf\u03bd\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u0301\u03c4\u03b5\u03c5\u03be\u03b7 \u03ba\u03c5\u0301\u03b7\u03c3\u03b7\u03c2: \u039c\u03b5\u03c4\u03b1\u0301 \u03b1\u03c0\u03bf\u0301 6 \u03ba\u03c5\u0301\u03ba\u03bb\u03bf\u03c5\u03c2 \u03b5\u03bd\u03b4\u03bf\u03bc\u03b7\u0301\u03c4\u03c1\u03b9\u03b1\u03c2 \u03c3\u03c0\u03b5\u03c1\u03bc\u03b1\u03c4\u03b5\u0301\u03b3\u03c7\u03c5\u03c3\u03b7\u03c2, \u03ba\u03c5\u0301\u03b7\u03c3\u03b7 \u03c0\u03b5\u0301\u03c4\u03c5\u03c7\u03b5 \u03c4\u03bf 25% \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03c9\u0301\u03bd > 35 \u03b5\u03c4\u03c9\u0301\u03bd \u03ba\u03b1\u03b9 52% \u03c4\u03c9\u03bd \u03b1\u03bd\u03b4\u03c1\u03c9\u0301\u03bd <35 \u03b5\u03c4\u03c9\u0301\u03bd (52% \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03bf\u0301- \u03c4\u03b7\u03c4\u03b1\u03c2 \u03ba\u03c5\u0301\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u0301 \u03c4\u03b1 35 \u03b5\u0301\u03c4\u03b7) (\u0392elloc et al., 2008). \u03a4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c0\u03b1\u0301\u03bd\u03c9 \u03b4\u03b5\u03b4\u03bf\u03bc\u03b5\u0301\u03bd\u03b1 \u03b4\u03b5\u03b9\u0301\u03c7\u03bd\u03bf\u03c5\u03bd \u03c0\u03c9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03c9\u03bd 30-35 \u03c6\u03b1\u03b9\u0301\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u0301\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03bf\u03bd \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03bd\u03b1 \u03b2\u03c1\u03b9\u0301\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1\u0301 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u0301\u03c0\u03b5\u03b4\u03b1. \u0391\u03c0\u03bf\u0301 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03c9\u03bd 35 \u03ba\u03b1\u03b9 \u03ba\u03c5\u03c1\u03b9\u0301\u03c9\u03c2 \u03b1\u03c0\u03bf\u0301 \u03b1\u03c5\u03c4\u03b7\u0301 \u03c4\u03c9\u03bd 40 \u03b5\u03c4\u03c9\u0301\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7- \u03c1\u03b5\u03b9\u0301\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03b7\u0301 \u03c0\u03c4\u03c9\u0301\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u0301\u03c4\u03b7\u03c4\u03b1\u03c2.<\/p>\n

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\u0397 \u03bc\u03b5\u03b3\u03b1\u03bb\u03c5\u0301\u03c4\u03b5\u03c1\u03b7 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03b5\u0301\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03b9\u0301 \u03bc\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03c5\u0301\u03c4\u03b5\u03c1\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03bf\u0301 \u03b4\u03b9\u03b1\u0301\u03c3\u03c4\u03b7\u03bc\u03b1 \u03b5\u0301\u03c9\u03c2
\n\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u0301\u03c4\u03b5\u03c5\u03be\u03b7 \u03ba\u03c5\u0301\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b1\u0301 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03c9\u0301\u03bd \u03ba\u03c5\u03b7\u0301\u03c3\u03b5\u03c9\u03bd.<\/p><\/blockquote>\n<\/div>\n

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\u0391\u03bb\u03bb\u03b1\u0301 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03b7\u0301 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u0301\u03b7\u03c3\u03b7 \u03b7 \u03b1\u03c5\u03be\u03b7\u03bc\u03b5\u0301\u03bd\u03b7 \u03c0\u03b1\u03c4\u03c1\u03b9\u03ba\u03b7\u0301 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u0301\u03c3\u03c4\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b1\u0301 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u0301\u03b7\u03c3\u03b7\u03c2, \u03b1\u0301\u03c3\u03c7\u03b5\u03c4\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03b5\u0301\u03b8\u03bf\u03b4\u03bf \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u0301\u03b8\u03b7\u03ba\u03b5 (IVF-ICSI), \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1, \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b1\u0301 \u03b5\u03bc\u03c6\u03c5\u0301\u03c4\u03b5\u03c5\u03c3\u03b7\u03c2, \u03c0\u03c4\u03c9\u03c7\u03b7\u0301 \u03b5\u03bc\u03b2\u03c1\u03c5\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03b7\u0301 \u03b5\u03be\u03b5\u0301\u03bb\u03b9\u03be\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u0301\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03c9\u03bd \u03b5\u03bc\u03b2\u03c1\u03c5\u0301\u03c9\u03bd (Opstal et al., 2021) \u03ba\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b1\u0301 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03c9\u0301\u03bd \u03ba\u03c5\u03b7\u0301\u03c3\u03b5\u03c9\u03bd (\u03b5\u0301\u03c9\u03c2 3% \u03bc\u03b5\u03b9\u0301\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03c9\u0301\u03bd \u03ba\u03c5\u03b7\u0301\u03c3\u03b5\u03c9\u03bd \u03b3\u03b9\u03b1 \u03ba\u03b1\u0301\u03b8\u03b5 \u03b5\u03c0\u03b9\u03c0\u03bb\u03b5\u0301\u03bf\u03bd \u03c7\u03c1\u03bf\u0301\u03bd\u03bf \u03c3\u03c4\u03b7 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1) (\u0397orta et al., 2019). \u03a4\u03b1 \u03b5\u03c5\u03c1\u03b7\u0301\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03bb\u03b1\u03b9\u03bf\u0301\u03c4\u03b5\u03c1\u03c9\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03c9\u0301\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u0301\u03c9\u03c3\u03b5 \u03c0\u03c1\u03bf\u0301\u03c3\u03c6\u03b1\u03c4\u03b1 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03c5\u03bc\u03b5\u0301\u03bd\u03b7 \u03bc\u03b5\u03bb\u03b5\u0301\u03c4\u03b7, \u03b7 \u03bf\u03c0\u03bf\u03b9\u0301\u03b1 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03b5\u0301\u03bb\u03b1\u03b2\u03b5 19.000 \u03c0\u03b5\u03c1\u03b9\u0301\u03c0\u03bf\u03c5 \u03ba\u03c5\u0301\u03ba\u03bb\u03bf\u03c5\u03c2 \u03b5\u03be\u03c9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03b7\u0301\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u0301\u03b7\u03c3\u03b7\u03c2: \u0397 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 >40 \u03b5\u03c4\u03c9\u0301\u03bd \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u0301\u03c3\u03c4\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u0301\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b1\u0301 \u03b3\u03b5\u03bd\u03bd\u03b7\u0301\u03c3\u03b5\u03c9\u03bd \u03b9\u03b4\u03b9\u03b1\u03b9\u0301\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03bf \u03b3\u03ba\u03c1\u03bf\u03c5\u03c0 \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03c9\u0301\u03bd 35-39 \u03b5\u03c4\u03c9\u0301\u03bd (Datta et al., 2022).<\/p>\n

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\u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03b1\u0301 \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03c5\u0301\u03c3\u03b1\u03bc\u03b5 \u03bd\u03b1 \u03c0\u03bf\u03c5\u0301\u03bc\u03b5 \u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03c5\u03c0\u03b1\u0301\u03c1\u03c7\u03b5\u03b9 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u0301 \u03c1\u03bf\u03bb\u03bf\u0301\u03b9. \u0391\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf \u00ab\u03c0\u03b1\u03c1\u03b1\u0301\u03b8\u03c5\u03c1\u03bf \u03b3\u03bf\u03bd\u03b9\u03bc\u03bf\u0301\u03c4\u03b7\u03c4\u03b1\u03c2\u00bb \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b3\u03c5\u03bd\u03b1\u03b9\u0301\u03ba\u03b1 \u03b5\u03b9\u0301\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u0301 \u03bc\u03b9\u03ba\u03c1\u03bf\u0301\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03bf\u0301 \u03b1\u03c5\u03c4\u03bf\u0301 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03b7 \u03b1\u03c1\u03bd\u03b7- \u03c4\u03b9\u03ba\u03b7\u0301 \u03b5\u03c0\u03b9\u0301\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03b5\u0301\u03bd\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03b9\u0301\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03b1\u0301\u03bd\u03b4\u03c1\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03b7\u0301 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03b7\u0301 \u03c4\u03bf\u03c5 \u03b6\u03b5\u03c5\u03b3\u03b1\u03c1\u03b9\u03bf\u03c5\u0301 \u03b5\u03b9\u0301\u03bd\u03b1\u03b9 \u03c0\u03bb\u03b5\u0301\u03bf\u03bd \u03b1\u03c0\u03bf\u03b4\u03b5\u03b4\u03b5\u03b9\u03b3\u03bc\u03b5\u0301\u03bd\u03b7.<\/p>\n

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\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03b9\u0301\u03b1<\/em><\/strong><\/h3>\n
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Araujo AB, Mohr BA, McKinlay JB, Changes in sexual function in middle-aged and older men: longitudinal data from the Massachu- setts Male Aging Study. J Am Geriatr Soc. 2004;52:1502-1509<\/p>\n

Belloc S, Cohen-Bacrie P, Benkhalifa M, Cohen-Bacrie M, De Mouzon J, Hazout A, Me\u0301ne\u0301zo Y. Effect of maternal and paternal age on pregnancy and miscarriage rates after intrauterine insemination. Reprod Biomed Online. 2008 Sep;17(3):392-7<\/p>\n

Cocuzza M, Athayde KS, Agarwal A, et al. Agerelated increase of reactive oxygen species in neat semen in healthy fertile men. Urology, 2008;71:490-494.<\/p>\n

Datta A.K, Campbell S, Diaz Fernandez R, Nargund G. Does advanced paternal age influence live birth rate independent of woman\u2019s age: analysis of 18, 825 fresh IVF\/ ICSI cycles from a national (HFEA) database.<\/p>\n

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Human Reproduction, Volume 37, Issue Supplement 1, July 2022<\/p>\n

Ford WC, North K, Taylor H, Increasing paternal age is associated with delayed conception in a large population of fertile couples: evidence for declining fecundity in older men. The ALSPAC Study Team (Avon Longitudinal Study of Pregnancy and Childhood) Hum Reprod. 2000;15:1703-170<\/p>\n

Harris I, Fronczak C, Roth L, Fertility and the Aging Male. Rev Urol. 2011;13(4): e184-e190<\/p>\n

Horta F, Vollenhoven B, Healey M, Busija L, Catt S, Temple-Smith P, Male ageing is negatively associated with the chance of live birth in IVF\/ICSI cycles for idiopathic infertility. Human Reproduction, Volume 34, Issue 12, December 2019, Pages 2523-2532<\/p>\n

Mahmoud AM, Goemaere S, El-Garem Y, et al., Testicular volume in relation to hormonal indices of gonadal function in community – dwelling elderly men. J Clin Endocrinol Metab. 2003;88:179-184<\/p>\n

Feldman HA, Longcope C, Derby CA, et al.<\/p>\n

Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study, J Clin Endocrinol Metab. 2002;87:589\u2013598<\/p>\n

Van Opstal J, Fieuws S, Spiessens C, Soubry A,<\/p>\n

Male age interferes with embryo growth in IVF treatment, Human Reproduction, Volume 36, Issue 1, January 2021, Pages 107\u2013115.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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 <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u039c\u03b1\u03c1\u03b9\u0301\u03bd\u03b1 \u0394\u03b7\u03bc\u03b7\u03c4\u03c1\u03b1\u0301\u03ba\u03b7 MD, MSc, M.H.A., PhD, EFOG-EBCOG, \u0393\u03c5\u03bd\u03b1\u03b9\u03ba\u03bf\u03bb\u03bf\u0301\u03b3\u03bf\u03c2 \u03a5\u03c0\u03bf\u03b2\u03bf\u03b7\u03b8\u03bf\u03c5\u0301\u03bc\u03b5\u03bd\u03b7\u03c2 \u0391\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b7\u0301\u03c2, European Fellow of Reproductive Medicine ESHRE\/EBCOG, \u0391\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03c9\u0301\u03c4\u03c1\u03b9\u03b1 \u0395\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03b7\u0301…<\/p>\n","protected":false},"author":2,"featured_media":22590,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[19,99,150],"tags":[],"class_list":["post-22587","post","type-post","status-publish","format-standard","has-post-thumbnail","category-blog-el","category-news-el","category-gonimotita"],"yoast_head":"\n\u03a0\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae - 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